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Kevin T Whelan Selected Research

Obesity

1/2008Discovery and structure-activity relationship of (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a selective serotonin 5-HT2C receptor agonist for the treatment of obesity.
3/2005Discovery and SAR of new benzazepines as potent and selective 5-HT(2C) receptor agonists for the treatment of obesity.

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Kevin T Whelan Research Topics

Disease

2Obesity
01/2008 - 03/2005
1Weight Gain
01/2008
1Cognitive Dysfunction
07/2003
1Seizures (Absence Seizure)
07/2003

Drug/Important Bio-Agent (IBA)

25-HT2C Serotonin ReceptorIBA
01/2008 - 03/2005
1Serotonin (5 Hydroxytryptamine)IBA
01/2008
1lorcaserinIBA
01/2008
1BenzazepinesIBA
03/2005
1LigandsIBA
07/2003
14- ((2- (1- methyl- 2- pyrrolidinyl)ethyl)thio)phenol hydrochlorideIBA
07/2003